Fascin anticorps

N° du produit ABIN6568972

L’anticorps Lapin Polyclonal anti-Fascin a été validé pour WB et IHC. Il convient pour détecter Fascin dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Fascin anticorps (ABIN6568972)

Antigène: Fascin (FSCN1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fascin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Fascin anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human FSCN1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Fascin

Antigène: Fascin (FSCN1)

Autre désignation: Fascin

Sujet:

Synonyms: 55 kDa actin bundling protein,55 kDa actin-bundling protein,Actin bundling protein,actin bundling protein,55-KD,FAN 1,FAN1,Fascin 1,Fascin actin bundling protein 1,Fascin,Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus),Fascin homolog 1,Fascin,sea urchin,homolog of,1,Fascin1,FLJ38511,FSCN 1,FSCN1,FSCN1,HSN,p55,Singed (Drosophila) like (sea urchin fascin homolog like),Singed drosophila homolog like,Singed like (fascin homolog sea urchin) (Drosophila),Singed like (fascin homolog sea urchin),Singed like protein,Singed,drosophila,homolog of,Singed-like protein,SNL,Strongylocentrotus purpuratus

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Poids moléculaire:

Observed_MW: 50kDa, 55kDa

Calculated_MW: 54kDa

ID gène: 6624

UniProt: Q16658